Título

Liver Biomarkers and Lipid Profiles in Mexican and Mexican-American 10- to 14-Year-Old Adolescents at Risk for Type 2 Diabetes

Autor

ANA CECILIA FERNANDEZ GAXIOLA

ROXANA VALDES RAMOS

Kimberly Fulda

ANA LAURA GUADARRAMA LOPEZ

BEATRIZ ELINA MARTINEZ CARRILLO

Susanna Franks

Shane Fernando

Nivel de Acceso

Acceso Abierto

Licencia

http://creativecommons.org/licenses/by-nc-nd/4.0

Materias

Diabetes Mellitus tipo 2 - ([2314-6753]) enzimas hepáticas - ([2314-6753]) perfil de lípidos - ([2314-6753]) adolescentes - ([2314-6753]) CIENCIAS SOCIALES - (CTI)

Resumen o descripción

Proyecto de investigación que describe la presencia de diversos factores de riesgo para desarrollar diabetes mellitus tipo 2 en adolescentes.

Liver enzymes alanine aminotransferase (ALT) and gamma glutamyl transferase (GGT) are markers for type 2 diabetes mellitus (T2DM); alkaline phosphatase is a marker of liver disease. Mexican-American adolescents are disproportionately affected by T2DM, while in Mexico its prevalence is emerging. We assessed liver biomarkers and lipid profiles among Mexican and Mexican-American adolescents 10–14 years old with high/low risk of T2DM through a cross-sectional, descriptive study (Texas n = 144; Mexico n = 149). We included family medical histories, anthropometry, and blood pressure. Obesity was present in one-third of subjects in both sites. ALT (UL) was higher (p < 0 001) in high-risk adolescents (23.5 ± 19.5 versus 17.2 ± 13.4 for males, 19.7 ± 11.6 versus 15.1 ± 5.5 for females), in Toluca and in Texas (26.0 ± 14.7 versus 20.0 ± 13.2 for males, 18.2 ± 13.4 versus 14.6 ± 10.1 for females), as well as GGT (UL) (p < 0 001) (18.7 ± 11.1 versus 12.4 ± 2.3 for males, 13.6 ± 5.8 versus 11.5 ± 3.9 for Mexican females; 21.0 ± 6.8 versus 15.4 ± 5.5 for males, 14.3 ± 5.0 versus 13.8 ± 5.3 for females in Texas). We found no differences by sex or BMI. Total cholesterol and HDL were higher among Mexican-Americans (p < 0 001). In conclusion, multiple risk factors were present in the sample. We found differences by gender and between high and low risk for T2DM adolescents in all liver enzymes in both sites.

Fondo Semilla UAEM-UNTHSC

Editor

HINDAWI

Fecha de publicación

26 de julio de 2017

Tipo de publicación

Artículo

Recurso de información

http://hdl.handle.net/20.500.11799/71031

Fuente

2314-6753

Idioma

Inglés

Audiencia

Estudiantes

Investigadores

Repositorio Orígen

REPOSITORIO INSTITUCIONAL DE LA UAEM

Descargas

410