Título
Thyroid function is associated with insulin resistance markers in healthy adolescents with risk factors to develop diabetes
Autor
JOSE DE JESUS GARDUÑO GARCIA
ENEIDA DEL SOCORRO CAMARILLO ROMERO
Ana Loe Ochoa
MARIA DEL SOCORRO ROMERO FIGUEROA
GABRIEL GERARDO HUITRON BRAVO
ROCIO TORRES GARCIA
Laura Patricia Montenegro Morales
Hugo Mendieta Zerón
Nivel de Acceso
Acceso Abierto
Materias
Resumen o descripción
Introduction: The prevalence of obesity and Type 2 diabetes mellitus (T2DM) among children and adolescents is rising. Thyroid function has been associated with insulin resistance. There is scarce information about how thyroid function could be related with cardiovascular risk or glucose homeostasis in adolescent. Aim: To analyze how thyroid function is associated with insulin resistance and another cardiovascular risk factors in healthy adolescents with risk factors to develop diabetes. Methods: A prospective cross-sectional analysis was carried out on euthyroid, adolescents. considered at high risk to develop Type 2 diabetes. Fasting blood samples were obtained. Thyroid function test and another cardiometabolic parameters were assessed. A 75 grams oral glucose tolerance test was performed to calculate insulin resistance. Results: One hundred adolescents were evaluated. The mean age was 15.9 ± 0.8 years, There is a negative correlation between Fasting insulin, post glucose load insulin and HOMA IR. There were no correlation with Matsuda index. We could not found any correlation with TSH values. Conclusions: We found a correlation between fasting insulin, HOMA IR and serum thyroid hormones, we did not find any relation with serum TSH. In euthyroid adolescents with risk factors to develop diabetes.
Editor
Diabetology
&
Metabolic Syndrome
Fecha de publicación
8 de marzo de 2015
Tipo de publicación
Artículo
Recurso de información
Fuente
1758-5996
Idioma
Inglés
Relación
7
16
Audiencia
Estudiantes
Investigadores
Repositorio Orígen
REPOSITORIO INSTITUCIONAL DE LA UAEM
Descargas
35