Título
Anti-Inflammatory activity and changes in antioxidant properties of leaf and stem extracts from Vitex mollis Kunth during in vitro digestions
Autor
JUAN ALFREDO MORALES DEL RIO
MELESIO GUTIERREZ LOMELI
MIGUEL ANGEL ROBLES GARCIA
JOSE ANTONIO AGUILAR LOPEZ
EUGENIA DEL CARMEN LUGO CERVANTES
PEDRO JAVIER GUERRERO MEDINA
SAUL RUIZ CRUZ
FRANCISCO JAVIER CINCO MOROYOQUI
FRANCISCO JAVIER WONG CORRAL
CARMEN LIZETTE DEL TORO SANCHEZ
Nivel de Acceso
Acceso Abierto
Resumen o descripción
"Vitex mollis is used in traditional Mexican medicine for the treatment of some ailments. However, there are no studies on what happens to the anti-inflammatory activity or antioxidant properties and total phenolic content of leaves and stem extracts of Vitex mollis during the digestion process; hence, this is the aim of this work. Methanolic, acetonic, and hexanic extracts were obtained from both parts of the plant. Extract yields and anti-inflammatory activity (elastase inhibition) were measured. Additionally, changes in antioxidant activity (DPPH and ABTS) and total phenols content of plant extracts before and after in vitro digestion were determined. The highest elastase inhibition to prevent inflammation was presented by hexanic extracts (leaf = 94.63% and stem = 98.30%). On the other hand, the major extract yield (16.14%), antioxidant properties (ABTS = 98.51% and DPPH = 94.47% of inhibition), and total phenols (33.70mg GAE/g of dried sample) were showed by leaf methanolic extract. Finally, leaf and stem methanolic extracts presented an antioxidant activity increase of 35.25% and 27.22%, respectively, in comparison to their initial values after in vitro digestion process. All samples showed a decrease in total phenols at the end of the digestion.These results could be the basis to search for new therapeutic agents from Vitex mollis."
Editor
Hindawi Publishing Corporation
Fecha de publicación
2015
Tipo de publicación
Artículo
Recurso de información
Formato
application/pdf
Fuente
Evidence-Based Complementary and Alternative Medicine Volume 2015, Article ID 349235
Audiencia
Estudiantes
Investigadores
Repositorio Orígen
Repositorio Institucional de CIATEJ
Descargas
375