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Association between nonalcoholic fatty liver disease and severe male reproductive organ impairment (Germinal Epithelial Loss): Study on a mouse model and on human patients

URIEL ALEJANDRO LOPEZ LEMUS RAQUEL GARZA GUAJARDO ORALIA BARBOZA QUINTANA ALEJANDRINA RODRIGUEZ HERNANDEZ José Guzmán Esquivel ALEJANDRO GARCÍA RIVERA VIOLETA M. MADRIGAL PÉREZ LAURA ELVIRA GARCÍA LABASTIDA ALEJANDRO DAVID SORIANO HERNANDEZ MARGARITA DE LA LUZ MARTINEZ FIERRO IRAM PABLO RODRIGUEZ SANCHEZ ELIZABETH SANCHEZ DUARTE ARIANA CABRERA LICONA GABRIEL CEJA ESPIRITU IVAN DELGADO ENCISO (2018)

Metabolic syndrome (MS) has been associated with testicular damage. Nonalcoholic fatty liver disease (NAFLD) is a multisystemic disease that affects different organs, but its effect on the testes is unknown. A study analyzing germ cell involvement on BALB/c mice was carried out. A parallel comparative study was conducted that investigated alterations in the germinal epithelium of male humans that died from an unrelated acute event. The complete medical histories and histologic samples of the thoracic aorta, liver tissue, and testicular tissue from the deceased subjects were collected. The degree of germinal epithelial loss (DGEL) was evaluated and the clinical and histologic data were compared between individuals with and without NAFLD. The only metabolic or morphologic variable that caused a significant difference in the DGEL, in both the animal model and humans, was the presence of liver steatosis. The percentage of steatosis was also correlated with the percentage of the DGEL. In humans, steatosis (greater than 20%) increased the risk 12-fold for presenting with a severe DGEL (OR: 12.5; 95% CI [1.2, 128.9]; p = .03). There was no association with age above 50 years or MS components. Steatosis grade was also correlated with atherosclerosis grade. NAFLD was a strongly associated factor implicated in severe DGEL, as well as the testis was identified as a probable target organ for damage caused by the disease. his finding could result in the search for new approach strategies in the management of men with fertility problems. Further studies are required to confirm these results.

Article

MEDICINA Y CIENCIAS DE LA SALUD Germ cells Atherosclerosis Testis Metabolic syndrome

“Mexico half way of making”: Carlos Chávez and the foundation of the National Institute of Fine Arts (INBA) (1945-1947)

Ana Garduño (2023)

I am focusing on the interaction between a cultural agent, Carlos Chávez, and the government elite, related to the circumstances of the enunciation of a public and official organism, INBA (The National Institute of Fine Arts), because I assume that political relations are fundamental to understand a process that endorsed the official culture as an appendage of politics. In spite of its relevance, this subject has not been studied. Based on archival documentation (at the National Archive of Mexico and the archive of INBA) I am examining the cultural policies derived from the foundation of INBA. Due to the current pandemic situation, it was not possible to consult other documental sources. I am formulating that the concept of “high culture” was at the core of a wider conflict between governmental interests and those of representative social actors, and I conclude that this obstacle would have conferred a major political and symbolical importance to the Institute, and consequently, would restrict its budget.

Article

Artículo

Carlos Chávez INBA Agentes culturales Políticas institucionales Centralización artística HUMANIDADES Y CIENCIAS DE LA CONDUCTA HUMANIDADES Y CIENCIAS DE LA CONDUCTA Foundation of the National Institute of Fine Arts in Mexico (INBA), Cultural agents Institutional policies Artistic centralization

Medición de flujo volumétrico en presas, canales y pozos

EDMUNDO PEDROZA-GONZALEZ VICTOR MANUEL ARROYO CORREA JULIO SERGIO SANTANA SEPULVEDA ARIOSTO AGUILAR CHAVEZ (2016)

Tabla de contenido: Introducción -- 1. El círculo de la medición efectiva -- 2. Medición en centrales hidroeléctricas -- 3. Medición en presas de almacenamiento -- 4. Introducción a la metrología en el contexto de la medición de agua -- 5. Medición de volúmenes, selección de una técnica.

Introducción -- 1. El círculo de la medición efectiva -- 2. Medición en centrales hidroeléctricas -- 3. Medición en presas de almacenamiento -- 4. Introducción a la metrología en el contexto de la medición de agua -- 5. Medición de volúmenes, selección de una técnica.

Book

Mediciones hidráulicas Medición de caudales Presas Pozos Centrales hidroeléctricas Telemetría INGENIERÍA Y TECNOLOGÍA

Estudio en modelo físico del funcionamiento hidráulico de la obra de excedencia del proyecto hidroeléctrico Arenal etapa I-II

Cecia Millán-Barrera LIDIA ZULEMA TOSTADO BOJORQUEZ WENDOLY FLORES ALARCON (2018)

El proyecto se conformó por las siguientes fases: 1. Calibración y ensayos preliminares – 2. Capacidad hidráulica y patrón del flujo – Conclusiones – Recomendaciones – Respuesta a las observaciones del informe final.

Working paper

Centrales hidroeléctricas Calibración Experimento de laboratorio INGENIERÍA Y TECNOLOGÍA

Thermal and mechanical properties of PLA-based multiscale cellulosic biocomposites

MIGUEL ANGEL RUZ CRUZ Pedro Jesús Herrera Franco Emmanuel Alejandro Flores Johnson MARIA VERONICA MORENO CHULIM LUCIANO MIGUEL GALERA MANZANO Alex Valadez González (2022)

In this work polylactic acid (PLA) based multiscale cellulosic biocomposites were prepared with the aim to evaluate the effect of the incorporation of cellulose nanocrystals (CNCs) on the PLA biocomposites reinforced with cellulose microfibers (MFCs). For this, PLA composite materials reinforced with both MFCs and with a combination of MFCs and CNCs were prepared, while keeping the content of cellulosic reinforcements constant. The thermal and mechanical properties of these multiscale PLA biocomposites were characterized by thermogravimetry (TGA), differential scanning calorimetry (DSC), flexural mechanical and, dynamic mechanical (DMA) tests. Likewise, they were characterized by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The results show that the replacement of MFCs by CNCs in the 1–5% range appreciably modifies the thermal and mechanical properties of multiscale compounds. For example, they increase the thermal stability of the materials, modify the PLA crystallization process and play the role of adhesion promoters since the mechanical properties in flexure increase in the order of 40% and the storage modulus increases in the order of 35% at room temperature. Also, the addition of CNCs increases the relaxation temperature of the material from 50 to 60 °C, thereby expanding the temperature range for its use. © 2022 The Author(s)

Article

MULTISCALE BIOCOMPOSITES CELLULOSE MICROFIBER CELLULOSE NANOCRYSTALS HIERARCHICAL STRUCTURE PROPERTIES INGENIERÍA Y TECNOLOGÍA CIENCIAS TECNOLÓGICAS TECNOLOGÍA DE MATERIALES PROPIEDADES DE LOS MATERIALES PROPIEDADES DE LOS MATERIALES

Transcriptome mining provides insights into cell wall metabolism and fiber lignification in Agave tequilana Weber

Luis Fernando Maceda Lopez ELSA BEATRIZ GONGORA CASTILLO Enrique Ibarra-Laclette DALIA C. MORAN VELAZQUEZ AMARANTA GIRON RAMIREZ Matthieu Bourdon José Luis Villalpando Aguilar Gabriela Chavez-Calvillo Toomer John Tang Parastoo Azadi Jorge Manuel Santamaría Fernández Itzel López-Rosas Mercedes G Lopez June Simpson FULGENCIO ALATORRE COBOS (2022)

Resilience of growing in arid and semiarid regions and a high capacity of accumulating sugar-rich biomass with low lignin percentages have placed Agave species as an emerging bioen-ergy crop. Although transcriptome sequencing of fiber-producing agave species has been explored, molecular bases that control wall cell biogenesis and metabolism in agave species are still poorly understood. Here, through RNAseq data mining, we reconstructed the cellulose biosynthesis pathway and the phenylpropanoid route producing lignin monomers in A. tequilana, and evaluated their expression patterns in silico and experimentally. Most of the orthologs retrieved showed differential expression levels when they were analyzed in different tissues with contrasting cellulose and lignin accumulation. Phylogenetic and structural motif analyses of putative CESA and CAD proteins allowed to identify those potentially involved with secondary cell wall formation. RT-qPCR assays revealed enhanced expression levels of AtqCAD5 and AtqCESA7 in parenchyma cells associated with extraxylary fibers, suggesting a mechanism of formation of sclerenchyma fibers in Agave similar to that reported for xylem cells in model eudicots. Overall, our results provide a framework for un-derstanding molecular bases underlying cell wall biogenesis in Agave species studying mechanisms involving in leaf fiber development in monocots. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.

Article

AGAVE CELL WALLS LIGNOCELLULOSE CAD PROTEIN CESA PROTEIN SCLERENCHYMA BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA GENÉTICA GENÉTICA MOLECULAR DE PLANTAS GENÉTICA MOLECULAR DE PLANTAS

Formulación del programa estratégico para la creación de un Centro Mexicano en Innovación en Energía Hidroeléctrica (CEMIE-HIDRO)

ANA ALICIA PALACIOS FONSECA (2017)

Se presentan los resultados del trabajo conjunto del Instituto Mexicano de Tecnología del Agua y el Instituto Nacional de Electricidad y Energías Limpias para la creación de un “Centro Mexicano de Innovación en Energía Hidroeléctrica”, a partir de tres ejes de desarrollo: 1) Caracterización y evaluación de los recursos; 2) Desarrollo de tecnología; y 3) Participación en el mercado.

Working paper

Centrales hidroeléctricas Energía hidroeléctrica INGENIERÍA Y TECNOLOGÍA