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Perfil epidemiológico y características clínicas de la escleritis en una población del noreste de México

YOLANDA MACIAS RODRIGUEZ (2022)

La epiescleritis (ESC) y escleritis (SC) son enfermedades que se caracterizan por causar inflamación de la capa externa fibrosa del globo ocular, la esclera y epiesclera. Estos padecimientos fueron descritos desde el siglo XIX y el Dr. Watson proporcionó la clasificación clínica que se usa para ordenarlas en sus diferentes subtipos. La etiología de las ESC y SC puede ser idiopática o asociada a causas específicas, como enfermedades autoinmunes, traumatismos, cirugías o infecciones. En diversas poblaciones del mundo se han reportado previamente las características de las ESC y SC. Sin embargo, en la población mexicana solo existen reportes de casos de presentaciones inusuales de ESC y SC y una sola serie reportando las características de la SC. Por lo anterior, se decidió llevar a cabo el presente estudio para expandir el conocimiento acerca de las características de la ESC y SC en la población mexicana. Se realizó un estudio retrospectivo y observacional. El diseño metodológico corresponde a una serie de casos. Se incluyeron pacientes con diagnóstico de ESC y SC, que hubieran firmado el consentimiento informado para participación en investigación clínica. Se analizaron los expedientes físicos y electrónicos de los pacientes que cumplieran con los criterios de inclusión, se tomó la información correspondiente a las variables previamente establecidas y se vació en una hoja de Microsoft Excel y posteriormente se analizaron estadísticamente con el programa SPSS (IBM). Se encontraron y analizaron 55 casos de ESC y 130 casos de SC. En ambos grupos hubo una predominancia del sexo femenino y la edad media fue mayor en pacientes con SC que en ESC (52.26 vs. 44.78 años). El tipo más común de ESC fue la simple y en SC la anterior difusa. La SC posterior fue el subtipo menos frecuente. La etiología más frecuente en ESC y SC fue la idiopática, y la segunda en frecuencia fue la espondiloartropatía asociada al haplotipo HLA B27 y la artritis reumatoide respectivamente. Los motivos de consulta más frecuente fueron ojo rojo solamente y ojo rojo doloroso. Los síntomas más comúnmente descritos por los pacientes con ESC y SC fueron ojo rojo, sensación de cuerpo extraño, dolor, lagrimeo y visión borrosa. Asimismo, los datos clínicos más comúnmente encontrados en pacientes con ESC y SC fueron la ingurgitción de los plexos conjuntivales y epiesclerales, queratopatía punteada superficial y queratitis ulcerativa periférica. La agudeza visual promedio fue buena tanto en ESC como en SC, siendo de 20/25 y 20/30 respectivamente. Para el análisis de tratamiento y recurrencias, se consideraron a los pacientes con un seguimiento mayor a una consulta, consistiendo estos últimos en 35 ESC y 108 SC. En la ESC, 91.4% de los pacientes fueron tratados con un AINE oral, 57.1% con esteroide tópico y 5.7% con AINE tópico. En SC, 76.9% usaron un AINE oral, 62% un esteroide oral, 50% un esteroide tópico y 52.7% un agente imnunosupresor. 29.6% de los pacientes con SC tuvieron una recurrencia. Al comparar la presente serie con las series de ESC y SC reportadas previamente en la literatura se encontró una considerable cantidad de similitudes, como la predominancia del sexo femenino, la media de edad, la incidencia estimada, los síntomas y signos, el tratamiento empleado y la cantidad de recurrencias y su asociación a una edad menor. Debido a todos lo anterior, se concluyó que la presentación de las ESC y SC en la población mexicana es similar a la presentación en otras poblaciones del mundo, previamente reportadas.

Especialidad en Oftalmología

Article

MEDICINA Y CIENCIAS DE LA SALUD CIENCIAS MÉDICAS CIENCIAS CLÍNICAS OFTALMOLOGÍA

The banana MaWRKY18, MaWRKY45, MaWRKY60 and MaWRKY70 genes encode functional transcription factors and display differential expression in response to defense phytohormones

SERGIO GARCIA LAYNES VIRGINIA AURORA HERRERA VALENCIA Lilia Guadalupe Tamayo Torres VERONICA LIMONES BRIONES FELIPE ALONSO BARREDO POOL FRAY MARTIN BAAS ESPINOLA Angel Alpuche-Solis CARLOS ALBERTO PUCH HAU SANTY PERAZA ECHEVERRIA (2022)

WRKY transcription factors (TFs) play key roles in plant defense responses through phytohormone signaling pathways. However, their functions in tropical fruit crops, especially in banana, remain largely unknown. Several WRKY genes from the model plants rice (OsWRKY45) and Arabidopsis (AtWRKY18, AtWRKY60, AtWRKY70) have shown to be attractive TFs for engineering disease resistance. In this study, we isolated four banana cDNAs (MaWRKY18, MaWRKY45, MaWRKY60, and MaWRKY70) with homology to these rice and Arabidopsis WRKY genes. The MaWRKY cDNAs were isolated from the wild banana Musa acuminata ssp. malaccensis, which is resistant to several diseases of this crop and is a progenitor of most banana cultivars. The deduced amino acid sequences of the four MaWRKY cDNAs revealed the presence of the conserved WRKY domain of ~60 amino acids and a zinc-finger motif at the N-terminus. Based on the number of WRKY repeats and the structure of the zinc-finger motif, MaWRKY18 and MaWRKY60 belong to group II of WRKY TFs, while MaWRKY45 and MaWRKY70 are members of group III. Their corresponding proteins were located in the nuclei of onion epidermal cells and were shown to be functional TFs in yeast cells. Moreover, expression analyses revealed that the majority of these MaWRKY genes were upregulated by salicylic acid (SA) or methyl jasmonate (MeJA) phytohormones, although the expression levels were relatively higher with MeJA treatment. The fact that most of these banana WRKY genes were upregulated by SA or MeJA, which are involved in systemic acquired resistance (SAR) or induced systemic resistance (ISR), respectively, make them interesting candidates for bioengineering broad-spectrum resistance in this crop. © 2022 by the authors.

Article

BANANA TRANSCRIPTION FACTOR WRKY DEFENSE PHYTOHORMONES SALICYLIC ACID METHYL JASMONATE SAR ISR BROAD-SPECTRUM RESISTANCE BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA GENÉTICA GENÉTICA MOLECULAR DE PLANTAS GENÉTICA MOLECULAR DE PLANTAS

The Banana MaWRKY18, MaWRKY45, MaWRKY60 and MaWRKY70 Genes Encode Functional Transcription Factors and Display Differential Expression in Response to Defense Phytohormones

SERGIO GARCIA LAYNES VIRGINIA AURORA HERRERA VALENCIA Lilia Guadalupe Tamayo Torres VERONICA LIMONES BRIONES FELIPE ALONSO BARREDO POOL FRAY MARTIN BAAS ESPINOLA Ángel Gabriel Alpuche Solís CARLOS ALBERTO PUCH HAU SANTY PERAZA ECHEVERRIA (2022)

"WRKY transcription factors (TFs) play key roles in plant defense responses through phytohormone signaling pathways. However, their functions in tropical fruit crops, especially in banana, remain largely unknown. Several WRKY genes from the model plants rice (OsWRKY45) and Arabidopsis (AtWRKY18, AtWRKY60, AtWRKY70) have shown to be attractive TFs for engineering disease resistance. In this study, we isolated four banana cDNAs (MaWRKY18, MaWRKY45, MaWRKY60, and MaWRKY70) with homology to these rice and Arabidopsis WRKY genes. The MaWRKY cDNAs were isolated from the wild banana Musa acuminata ssp. malaccensis, which is resistant to several diseases of this crop and is a progenitor of most banana cultivars. The deduced amino acid sequences of the four MaWRKY cDNAs revealed the presence of the conserved WRKY domain of ~60 amino acids and a zinc-finger motif at the N-terminus. Based on the number of WRKY repeats and the structure of the zinc-finger motif, MaWRKY18 and MaWRKY60 belong to group II of WRKY TFs, while MaWRKY45 and MaWRKY70 are members of group III. Their corresponding proteins were located in the nuclei of onion epidermal cells and were shown to be functional TFs in yeast cells. Moreover, expression analyses revealed that the majority of these MaWRKY genes were upregulated by salicylic acid (SA) or methyl jasmonate (MeJA) phytohormones, although the expression levels were relatively higher with MeJA treatment. The fact that most of these banana WRKY genes were upregulated by SA or MeJA, which are involved in systemic acquired resistance (SAR) or induced systemic resistance (ISR), respectively, make them interesting candidates for bioengineering broad-spectrum resistance in this crop."

Article

Banana Transcription factor WRKY Defense phytohormones Salicylic acid Methyl jasmonate SAR ISR Broad-spectrum resistance BIOLOGÍA Y QUÍMICA CIENCIAS DE LA VIDA GENÉTICA GENÉTICA

Addressing agricultural labour issues is key to biodiversity-smart farming

Thomas Daum Frédéric Baudron Matin Qaim Ingo Grass (2023)

There is an urgent need for agricultural development strategies that reconcile agricultural production and biodiversity conservation. This is especially true in the Global South where population growth is rapid and much of the world's remaining biodiversity is located. Combining conceptual thoughts with empirical insights from case studies in Indonesia and Ethiopia, we argue that such strategies will have to pay more attention to agricultural labour dynamics. Farmers have a strong motivation to reduce the heavy toil associated with farming by adopting technologies that save labour but can negatively affect biodiversity. Labour constraints can also prevent farmers from adopting technologies that improve biodiversity but increase labour intensity. Without explicitly accounting for labour issues, conservation efforts can hardly be successful. We hence highlight the need for biodiversity-smart agriculture, that is farming practices or systems that reconcile biodiversity with land and labour productivity. Our empirical insights suggest that technological and institutional options to reconcile farmers' socio-economic goals and biodiversity conservation exist but that more needs to be done to implement such options at scale.

Article

Land Sharing Trade-Offs CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA AGRICULTURAL DEVELOPMENT BIODIVERSITY CONSERVATION LABOUR SUSTAINABILITY

Influencia de las fases lunares en fertilidad, tasa de preñez y partos de vacas mestizas en el trópico seco.

CANUTO MUÑOZ GARCIA ROSENDO CUICAS HUERTA JUAN GONZALEZ MALDONADO EFREN ESTRADA PAQUI ISIDRO JAUREGUI PLATA JULIO CESAR GOMEZ VARGAS (2023)

There is speculation about moon phases influencing animal reproductive performance. A study was carried out to shed light on the influence of moon phases on estrus presentation, pregnancy rate, calving presentation, and offspring sex in cows from the Mexican dry tropical region. The reproductive data of 580 crossbred cows from 2010 to 2021 was organized according to reproductive events (estrus presentation, gestation, calving presentation, and offspring sex) occurrence during moon phases (new moon, first quarter, full moon, and last quarter). The data were analyzed by Chi-squared test and logistic regression. The full moon reduced the estrus presentation (p0.05). It is concluded that the full moon reduces estrus presentation in crossbred cows. Moon phases do not influence the gestation, calving presentation, and offspring sex.

Article

estrus calving offspring sex CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA CIENCIAS AGRARIAS CIENCIAS VETERINARIAS FISIOLOGÍA ANIMAL

Análisis de las conexiones matemáticas en la enseñanza y aprendizaje de la derivada basado en un networking of theories entre la Teoría de las conexiones y el Enfoque ontosemiótico.

CAMILO ANDRES RODRIGUEZ NIETO (2021)

Consejo Nacional de Ciencia y Tecnología No. 602990

In research in Mathematics Education, models have been reported to analyze mathematical connections in which specific connection categories are considered. In the literature, it was identified that the most used model is the Businskas with contributions from other researchers. However, the problem refers to the fact that some categories of connections limit the analysis of mathematical activity and, therefore, the research suggests that the established categories are validated and, if possible, new categories of connections are reported. Other investigations focused on exploring mathematical connections and understanding the derivative reveal that high school students, pre-service teachers, and some in-service mathematics teachers have difficulty connecting multiple representations of the derivative (e.g., algebraic, or symbolic, verbal, graphic, tabular) and establish connections between partial meanings about this concept.

Doctoral thesis

Networking of theories Mathematical connections Onto-semiotic approach semiotic function derivative teacher students HUMANIDADES Y CIENCIAS DE LA CONDUCTA PEDAGOGÍA TEORÍA Y MÉTODOS EDUCATIVOS TEORÍAS EDUCATIVAS

Intimate partner violence and its relationship to labor income

Yei Javier Zepeda Hernández Alma Sofia Santillan (2024)

In Mexico, 70.1% of women have been victims of violence in their lifetime and the main perpetrator is her intimate partner. Gender violence is a public health problem that has multiple negative impacts in woman and their offsprings. The relation violence and income is an issue that has been scarcely studied for Mexico. The objective of this article is to analyze the intimate partner violence and its relationship to labor income for Mexican women, data used are from the National Survey on the Dynamics of Households Relationships (ENDIREH 2021). The principal component method is used to estimate five kinds of violence; physical, emotional, economic, sexual and, harassment. The instrumental variables method is used to consider the endogeneity of income and violence variables. Except harassment, the results indicate a negative relationship between income and violence. Specifically, sexual violence has the greatest negative effects; women who are victims of sexual violence have an average reduction of 17.4% in monthly labor income. This negative effect represents a loss of just over two month of working days per year and, in the aggregate terms, is equivalent to 0.87% of GDP. The above highlights the importance of orienting public policy actions to work in prevention, attention, punishment and eradications any kind of violence against women. 

Article

Artículo

Intimate partner violence Labor income Endogeneity Instrumental variables Cost of violence Violencia de pareja Ingresos laborales Endogeneidad Variables instrumentales Costo de la violencia. CIENCIAS SOCIALES CIENCIAS SOCIALES

Urban muralism in cities and towns of Chiapas. Configuring collective experiences and recovering urban spaces

Maria de Lourdes Morales Vargas (2023)

This article expresses some reflections on the practice of urban muralism and the result of the approach to urban muralism projects or initiatives that have taken place in some cities, towns and villages in the state of Chiapas. This approach has made it possible to describe the dynamics, forms of participation, processes and agents that participate in the configuration and collective expression of urban murals in these spaces. From descriptive ethnography and its tools it was possible to approach the experiences of urban intervention that coexist with the community, in streets, parks, business walls, houses. This has made it possible to understand the practice of urban muralism as an artistic, collective, community process, a project of regeneration or urban recovery and as a practice of symbolic production of incidence in the space where it is implanted, configuring multiple experiences.

Article

Artículo

URBAN MURALISM URBAN MURAL YOUTH CREATIVE PRACTICES RECOVERY OF URBAN SPACES muralismo urbano, mural urbano, arte calle, practicas creativas juveniles, proceso artístico. CIENCIAS SOCIALES; HUMANIDADES Y CIENCIAS DE LA CONDUCTA CIENCIAS SOCIALES HUMANIDADES Y CIENCIAS DE LA CONDUCTA

Panorama de la desaparición de personas en Guerrero, 2015-2021.

GABINO SOLANO RAMIREZ (2023)

This work offers a general overview of the disappearance of persons in Guerrero during the period 2015- 2021 seen from the reports published in the local press, and some national media. The objective is to make visible this serious social problem, considered a crime against humanity and of the greatest concern for families and citizens who perceive the feeling of impunity and insecurity. The study follows up on basic indicators of the victims of disappearance, such as the modality (kidnapping, uprising, confrontation, and home invasion), general characteristics of the victims, alleged perpetrators, places and circumstances of the event. Considering the phenomenon as a public issue, the work aims to raise awareness among the population and institutional structures to motivate the generation of strategies to help prevent these disappearances.

Article

Forced Disappearance of Persons Criminal Violence Guerrero pi.evi-UAGro newspaper library CIENCIAS SOCIALES CIENCIA POLÍTICA SOCIOLOGÍA POLÍTICA CONFLICTOS SOCIALES