Título

Association of extrapituitary prolactin promoter polymorphism with disease susceptibility and anti-RNP antibodies in Mexican patients with systemic lupus erythematosus.

Autor

JORGE HERNANDEZ BELLO

CLAUDIA AZUCENA PALAFOX SANCHEZ

SAMUEL GARCIA ARELLANO

ZYANYA REYES CASTILLO

ANA LAURA PEREIRA SUAREZ

ISELA PARRA ROJAS

JOSE EDUARDO NAVARRO ZARZA

ULISES DE LA CRUZ MOSSO

NORA MAGDALENA TORRES CARRILLO

Jose Francisco Muñoz Valle

Nivel de Acceso

Acceso Abierto

Licencia

http://creativecommons.org/licenses/by-nc-nd/4.0

Materias

systemic lupus erythematosus prolactin, BIOLOGÍA Y QUÍMICA - (CTI) CIENCIAS DE LA VIDA - (CTI) OTRAS ESPECIALIDADES DE LA BIOLOGÍA - (CTI)

Resumen o descripción

Prolactin (PRL) is a 23-kDa protein that can be synthesized and secreted by pituitary and extrapituitary tissues such as immune cells due to its expression being regulated by two independent promoter regions. The promoter which is responsible for extrapituitary expression contains the single nucleotide polymorphism (SNP) ¿1149 G/T previously associated with autoimmune diseases in various populations. This study evaluates the relationship of PRL ¿1149 G/T polymorphism with PRL serum levels and clinical characteristics in systemic lupus erythematosus (SLE) patients from western Mexico.

Editor

Archives of Medical Science

Fecha de publicación

21 de junio de 2016

Tipo de publicación

Artículo

Recurso de información

http://ri.uagro.mx/handle/uagro/1185

Formato

application/pdf

Idioma

Español

Audiencia

Público en general

Repositorio Orígen

Repositorio Institucional de Ciencia Abierta de la Universidad Autónoma de Guerrero

Descargas

0