Título
Nitazoxanide against COVID-19 in three explorative scenarios
Autor
José Meneses Calderón
María del Rocío Figueroa Flores
Leopoldo Paniagua Coria
JESÚS CARLOS BRIONES GARDUÑO
Jazmín Meneses Figueroa
María José Vargas Contreras
Lilia de la Cruz
Salvador Díaz Meza
REYNALDO RAMIREZ CHACON
Srivatsan Padmanabhan
Hugo Mendieta Zerón
Nivel de Acceso
Acceso Abierto
Materias
Resumen o descripción
to describe the results of treating COVID-19 positive patients with nitazoxanide in three clinical settings: pregnancy/puerperium, hospitalized patients in an Internal Medicine Service and in an ambulatory setting. Methodology: This was a prospective follow-up and report of COVID-19 cases in three different situations, pregnant women, hospitalized patients receiving medical attention in an Internal Medicine Service and ambulatory patients residing in Toluca City, and Mexico City. Results: The experience with a first group of 20 women, pregnant (17) or in immediate puerperium (3) was successful in 18 cases with two unfortunate deaths. The five cases treated in an Internal Medicine service showed a positive outcome with two patients weaned from mechanical ventilation. Of the remaining 16 patients treated in an ambulatory setting, all got cured. Nitazoxanide seems to be useful against SARS-CoV-2, not only in an early intervention but also in critical condition as well as in pregnancy without undesired effects for the babies. As an adjunctive therapy budesonide was used that seems to contribute to the clinical improvement. Conclusions: Nitazoxanide could be useful against COVID-19 as a safe and available regimen to be tested in a massive way immediately.
Editor
The Journal of Infection in Developing Countries
Fecha de publicación
7 de octubre de 2020
Tipo de publicación
Artículo
Recurso de información
Fuente
2036-6590
Idioma
Inglés
Relación
14
9
Audiencia
Estudiantes
Investigadores
Repositorio Orígen
REPOSITORIO INSTITUCIONAL DE LA UAEM
Descargas
182