Título
Synthesis of copper nanoparticles stabilized with organic ligands and their antimicrobial properties
Autor
Noemi Jardon Maximino
Marissa Pérez Alvarez
gregorio cadenas_pliego
Luis Edmundo Lugo Uribe
Colaborador
Jose M Mata-Padilla
Enrique Díaz Barriga Castro
Nivel de Acceso
Acceso Abierto
Referencia de publicación
ISSN/2073-4360
URL/https://www.mdpi.com/2073-4360/13/17/2846
URL/https://www.mdpi.com/journal/polymers
Materias
Chemical reduction method - (PALABRA CLAVE DEL AUTOR) Copper nanoparticles - (PALABRA CLAVE DEL AUTOR) Polyethylenimine - (PALABRA CLAVE DEL AUTOR) Zeta potential - (PALABRA CLAVE DEL AUTOR) Antimicrobial - (PALABRA CLAVE DEL AUTOR) INGENIERÍA Y TECNOLOGÍA - (CTI) CIENCIAS TECNOLÓGICAS - (CTI) TECNOLOGÍA METALÚRGICA - (CTI) COBRE - (CTI) COBRE - (CTI)
Resumen o descripción
In this work, we report the synthesis of copper nanoparticles (Cu NPs), employing the chemical reduction method in an aqueous medium. We used copper sulfate pentahydrate (CuSO45H2O) as a metallic precursor; polyethylenimine (PEI), allylamine (AAM), and 4-aminobutyric acid (AABT) as stabilizing agents; and hydrated hydrazine as a reducing agent. The characterization of the obtained nanoparticles consisted of X-ray, TEM, FTIR, and TGA analyses. Through these techniques, it was possible to detect the presence of the used stabilizing agents on the surface of the NPs. Finally, a zeta potential analysis was performed to differentiate the stability of the nanoparticles with a different type of stabilizing agent, from which it was determined that the most stable nanoparticles were the Cu NPs synthesized in the presence of the PEI/AAM mixture. The antimicrobial activity of Cu/PEI/AABT toward P. aeruginosa and S. aureus bacteria was high, inhibiting both bacteria with low contact times and copper concentrations of 50–200 ppm. The synthesis method allowed us to obtain Cu NPs free of oxides, stable to oxidation, and with high yields. The newly functionalized Cu NPs are potential candidates for antimicrobial applications.
Author contributions: Conceptualization, G.C.-P., N.J.-M., M.P.-A., C.C.-A. and L.E.L.-U.; methodology, N.J.-M., M.P.-A., L.E.L.-U., E.D.B.-C., C.C.-A. and J.M.M.-P.; formal analysis, J.M.M.-P., M.P.-A., E.D.B.-C., C.C.-A. and N.J.-M.; investigation, G.C.-P., J.M.M.-P., L.E.L.-U., C.C.-A. and M.P.-A.; writing—original draft preparation, N.J.-M., G.C.-P., M.P.-A. and L.E.L.-U.; writing—review and editing, N.J.-M., M.P.-A. and G.C.-P. All authors have read and agreed to the published version of the manuscript.
Funding: This research was funded by CONACyT-SENER-Sustentabilidad Energética, CentroMexicano de Innovación en Energía del OcéanoGrantNo. 0249795 and FORDECYT-PRONACES/845101/2020, grant number 845101.
Institutional Review Board Statement: Not applicable.
Informed consent statement: Not applicable.
Data availability statement: The data presented in this study are available on request from the corresponding author.
Acknowledgments: Noemi Jardón-Maximino would like to thank CONACYT for Scholarship no. 263275. The authors would also like to thank G. Mendez Padilla, A. Espinoza Muñoz, V.E. Comparán-Padilla, J.A. Mercado Silva, J. Campos Oyervides, and R. Cedillo García for their valuable technical support.
Conflicts of interest: The authors declare no conflict of interest.
Editor
MDPI
Fecha de publicación
2021
Tipo de publicación
Artículo
Versión de la publicación
Versión publicada
Recurso de información
Formato
application/pdf
Fuente
polymers, vol. 13, no. 17, art. 2846
Idioma
Inglés
Relación
&
Barriga-Castro, E. D. (2021). Synthesis of copper nanoparticles stabilized with organic ligands and their antimicrobial properties. Polymers, 13(17), 2846. https://doi.org/10.3390/polym13172846
Audiencia
Público en general
Sugerencia de citación
Jardón-Maximino, N., Pérez-Alvarez, M., Cadenas-Pliego, G., Lugo-Uribe, L. E., Cabello-Alvarado, C., Mata-Padilla, J. M.,
Repositorio Orígen
CIATEQ Digital
Descargas
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