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Perfil epidemiológico y características clínicas de la escleritis en una población del noreste de México

YOLANDA MACIAS RODRIGUEZ (2022)

La epiescleritis (ESC) y escleritis (SC) son enfermedades que se caracterizan por causar inflamación de la capa externa fibrosa del globo ocular, la esclera y epiesclera. Estos padecimientos fueron descritos desde el siglo XIX y el Dr. Watson proporcionó la clasificación clínica que se usa para ordenarlas en sus diferentes subtipos. La etiología de las ESC y SC puede ser idiopática o asociada a causas específicas, como enfermedades autoinmunes, traumatismos, cirugías o infecciones. En diversas poblaciones del mundo se han reportado previamente las características de las ESC y SC. Sin embargo, en la población mexicana solo existen reportes de casos de presentaciones inusuales de ESC y SC y una sola serie reportando las características de la SC. Por lo anterior, se decidió llevar a cabo el presente estudio para expandir el conocimiento acerca de las características de la ESC y SC en la población mexicana. Se realizó un estudio retrospectivo y observacional. El diseño metodológico corresponde a una serie de casos. Se incluyeron pacientes con diagnóstico de ESC y SC, que hubieran firmado el consentimiento informado para participación en investigación clínica. Se analizaron los expedientes físicos y electrónicos de los pacientes que cumplieran con los criterios de inclusión, se tomó la información correspondiente a las variables previamente establecidas y se vació en una hoja de Microsoft Excel y posteriormente se analizaron estadísticamente con el programa SPSS (IBM). Se encontraron y analizaron 55 casos de ESC y 130 casos de SC. En ambos grupos hubo una predominancia del sexo femenino y la edad media fue mayor en pacientes con SC que en ESC (52.26 vs. 44.78 años). El tipo más común de ESC fue la simple y en SC la anterior difusa. La SC posterior fue el subtipo menos frecuente. La etiología más frecuente en ESC y SC fue la idiopática, y la segunda en frecuencia fue la espondiloartropatía asociada al haplotipo HLA B27 y la artritis reumatoide respectivamente. Los motivos de consulta más frecuente fueron ojo rojo solamente y ojo rojo doloroso. Los síntomas más comúnmente descritos por los pacientes con ESC y SC fueron ojo rojo, sensación de cuerpo extraño, dolor, lagrimeo y visión borrosa. Asimismo, los datos clínicos más comúnmente encontrados en pacientes con ESC y SC fueron la ingurgitción de los plexos conjuntivales y epiesclerales, queratopatía punteada superficial y queratitis ulcerativa periférica. La agudeza visual promedio fue buena tanto en ESC como en SC, siendo de 20/25 y 20/30 respectivamente. Para el análisis de tratamiento y recurrencias, se consideraron a los pacientes con un seguimiento mayor a una consulta, consistiendo estos últimos en 35 ESC y 108 SC. En la ESC, 91.4% de los pacientes fueron tratados con un AINE oral, 57.1% con esteroide tópico y 5.7% con AINE tópico. En SC, 76.9% usaron un AINE oral, 62% un esteroide oral, 50% un esteroide tópico y 52.7% un agente imnunosupresor. 29.6% de los pacientes con SC tuvieron una recurrencia. Al comparar la presente serie con las series de ESC y SC reportadas previamente en la literatura se encontró una considerable cantidad de similitudes, como la predominancia del sexo femenino, la media de edad, la incidencia estimada, los síntomas y signos, el tratamiento empleado y la cantidad de recurrencias y su asociación a una edad menor. Debido a todos lo anterior, se concluyó que la presentación de las ESC y SC en la población mexicana es similar a la presentación en otras poblaciones del mundo, previamente reportadas.

Especialidad en Oftalmología

Article

MEDICINA Y CIENCIAS DE LA SALUD CIENCIAS MÉDICAS CIENCIAS CLÍNICAS OFTALMOLOGÍA

Association between nonalcoholic fatty liver disease and severe male reproductive organ impairment (Germinal Epithelial Loss): Study on a mouse model and on human patients

URIEL ALEJANDRO LOPEZ LEMUS RAQUEL GARZA GUAJARDO ORALIA BARBOZA QUINTANA ALEJANDRINA RODRIGUEZ HERNANDEZ José Guzmán Esquivel ALEJANDRO GARCÍA RIVERA VIOLETA M. MADRIGAL PÉREZ LAURA ELVIRA GARCÍA LABASTIDA ALEJANDRO DAVID SORIANO HERNANDEZ MARGARITA DE LA LUZ MARTINEZ FIERRO IRAM PABLO RODRIGUEZ SANCHEZ ELIZABETH SANCHEZ DUARTE ARIANA CABRERA LICONA GABRIEL CEJA ESPIRITU IVAN DELGADO ENCISO (2018)

Metabolic syndrome (MS) has been associated with testicular damage. Nonalcoholic fatty liver disease (NAFLD) is a multisystemic disease that affects different organs, but its effect on the testes is unknown. A study analyzing germ cell involvement on BALB/c mice was carried out. A parallel comparative study was conducted that investigated alterations in the germinal epithelium of male humans that died from an unrelated acute event. The complete medical histories and histologic samples of the thoracic aorta, liver tissue, and testicular tissue from the deceased subjects were collected. The degree of germinal epithelial loss (DGEL) was evaluated and the clinical and histologic data were compared between individuals with and without NAFLD. The only metabolic or morphologic variable that caused a significant difference in the DGEL, in both the animal model and humans, was the presence of liver steatosis. The percentage of steatosis was also correlated with the percentage of the DGEL. In humans, steatosis (greater than 20%) increased the risk 12-fold for presenting with a severe DGEL (OR: 12.5; 95% CI [1.2, 128.9]; p = .03). There was no association with age above 50 years or MS components. Steatosis grade was also correlated with atherosclerosis grade. NAFLD was a strongly associated factor implicated in severe DGEL, as well as the testis was identified as a probable target organ for damage caused by the disease. his finding could result in the search for new approach strategies in the management of men with fertility problems. Further studies are required to confirm these results.

Article

MEDICINA Y CIENCIAS DE LA SALUD Germ cells Atherosclerosis Testis Metabolic syndrome

Addressing agricultural labour issues is key to biodiversity-smart farming

Thomas Daum Frédéric Baudron Matin Qaim Ingo Grass (2023)

There is an urgent need for agricultural development strategies that reconcile agricultural production and biodiversity conservation. This is especially true in the Global South where population growth is rapid and much of the world's remaining biodiversity is located. Combining conceptual thoughts with empirical insights from case studies in Indonesia and Ethiopia, we argue that such strategies will have to pay more attention to agricultural labour dynamics. Farmers have a strong motivation to reduce the heavy toil associated with farming by adopting technologies that save labour but can negatively affect biodiversity. Labour constraints can also prevent farmers from adopting technologies that improve biodiversity but increase labour intensity. Without explicitly accounting for labour issues, conservation efforts can hardly be successful. We hence highlight the need for biodiversity-smart agriculture, that is farming practices or systems that reconcile biodiversity with land and labour productivity. Our empirical insights suggest that technological and institutional options to reconcile farmers' socio-economic goals and biodiversity conservation exist but that more needs to be done to implement such options at scale.

Article

Land Sharing Trade-Offs CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA AGRICULTURAL DEVELOPMENT BIODIVERSITY CONSERVATION LABOUR SUSTAINABILITY

Influencia de las fases lunares en fertilidad, tasa de preñez y partos de vacas mestizas en el trópico seco.

CANUTO MUÑOZ GARCIA ROSENDO CUICAS HUERTA JUAN GONZALEZ MALDONADO EFREN ESTRADA PAQUI ISIDRO JAUREGUI PLATA JULIO CESAR GOMEZ VARGAS (2023)

There is speculation about moon phases influencing animal reproductive performance. A study was carried out to shed light on the influence of moon phases on estrus presentation, pregnancy rate, calving presentation, and offspring sex in cows from the Mexican dry tropical region. The reproductive data of 580 crossbred cows from 2010 to 2021 was organized according to reproductive events (estrus presentation, gestation, calving presentation, and offspring sex) occurrence during moon phases (new moon, first quarter, full moon, and last quarter). The data were analyzed by Chi-squared test and logistic regression. The full moon reduced the estrus presentation (p0.05). It is concluded that the full moon reduces estrus presentation in crossbred cows. Moon phases do not influence the gestation, calving presentation, and offspring sex.

Article

estrus calving offspring sex CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA CIENCIAS AGRARIAS CIENCIAS VETERINARIAS FISIOLOGÍA ANIMAL

Análisis de las conexiones matemáticas en la enseñanza y aprendizaje de la derivada basado en un networking of theories entre la Teoría de las conexiones y el Enfoque ontosemiótico.

CAMILO ANDRES RODRIGUEZ NIETO (2021)

Consejo Nacional de Ciencia y Tecnología No. 602990

In research in Mathematics Education, models have been reported to analyze mathematical connections in which specific connection categories are considered. In the literature, it was identified that the most used model is the Businskas with contributions from other researchers. However, the problem refers to the fact that some categories of connections limit the analysis of mathematical activity and, therefore, the research suggests that the established categories are validated and, if possible, new categories of connections are reported. Other investigations focused on exploring mathematical connections and understanding the derivative reveal that high school students, pre-service teachers, and some in-service mathematics teachers have difficulty connecting multiple representations of the derivative (e.g., algebraic, or symbolic, verbal, graphic, tabular) and establish connections between partial meanings about this concept.

Doctoral thesis

Networking of theories Mathematical connections Onto-semiotic approach semiotic function derivative teacher students HUMANIDADES Y CIENCIAS DE LA CONDUCTA PEDAGOGÍA TEORÍA Y MÉTODOS EDUCATIVOS TEORÍAS EDUCATIVAS

Farmers’ perspectives as determinants for adoption of conservation agriculture practices in Indo-Gangetic Plains of India

Ajay Kumar Mishra ML JAT (2022)

Understanding the farmer's perspective has traditionally been critical to influencing the adoption and out-scaling of CA-based climate-resilient practices. The objective of this study was to investigate the biophysical, socio-economic, and technical constraints in the adoption of CA by farmers in the Western- and Eastern-IGP, i.e., Karnal, Haryana, and Samastipur, Bihar, respectively. A pre-tested structured questionnaire was administered to 50 households practicing CA in Western- and Eastern-IGP. Smallholder farmers (<2 ha of landholding) in Karnal are 10% and Samastipur 66%. About 46% and 8% of households test soil periodically in Karnal and Samastipur, respectively. Results of PCA suggest economic profitability and soil health as core components from the farmer's motivational perspective in Karnal and Samastipur, respectively. Promotion and scaling up of CA technologies should be targeted per site-specific requirements, emphasizing biophysical resource availability, socio-economic constraints, and future impacts of such technology.

Article

Smallholder Farmers Agents of Change Technology Diffusion Climate-Smart Practices CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA SMALLHOLDERS SOCIAL STRUCTURE IRRIGATION MANAGEMENT TECHNOLOGY CLIMATE-SMART AGRICULTURE CONSERVATION AGRICULTURE

Intimate partner violence and its relationship to labor income

Yei Javier Zepeda Hernández Alma Sofia Santillan (2024)

In Mexico, 70.1% of women have been victims of violence in their lifetime and the main perpetrator is her intimate partner. Gender violence is a public health problem that has multiple negative impacts in woman and their offsprings. The relation violence and income is an issue that has been scarcely studied for Mexico. The objective of this article is to analyze the intimate partner violence and its relationship to labor income for Mexican women, data used are from the National Survey on the Dynamics of Households Relationships (ENDIREH 2021). The principal component method is used to estimate five kinds of violence; physical, emotional, economic, sexual and, harassment. The instrumental variables method is used to consider the endogeneity of income and violence variables. Except harassment, the results indicate a negative relationship between income and violence. Specifically, sexual violence has the greatest negative effects; women who are victims of sexual violence have an average reduction of 17.4% in monthly labor income. This negative effect represents a loss of just over two month of working days per year and, in the aggregate terms, is equivalent to 0.87% of GDP. The above highlights the importance of orienting public policy actions to work in prevention, attention, punishment and eradications any kind of violence against women. 

Article

Artículo

Intimate partner violence Labor income Endogeneity Instrumental variables Cost of violence Violencia de pareja Ingresos laborales Endogeneidad Variables instrumentales Costo de la violencia. CIENCIAS SOCIALES CIENCIAS SOCIALES